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Sue Palumbo's avatar

I went to veterinary school in the Philippines in the early 80’s. At the time there were more human deaths in the PI than any other countries. We were all vaccinated. There was a study I remember that flushing out human bites wounds prevented rabies transmission from infected animals. Of course I would get post exposure prophylaxis. Just saying we underestimate the value of dilution with infectious disease transmission. Americans seem to feel as if rabies is not a threat to us. How wrong we are.

Thomas Boo's avatar

Hi Matt, hope you’re well. I value the bulletins—keep up the good work!

Agree with Dr Palomo on the value of local wound care, when a bite is recognized! It's the bat exposure without known physical contact recs that I struggle with in terms of public health effectiveness.

According to the abstract of a 2007 report in Clinical Infectious Diseases by De Serres et al., the incidence of human rabies associated with sharing space with bats while sleeping, without known physical contact, was 0.6 cases per billion person-years and there is no evidence that bat-associated rabies incidence has decreased since these ACIP/CDC recs were introduced decades ago. The number needed to treat is astonishingly high, as would be costs, of course.

It's a tough one on an individual level: PEP as a preventive intervention is super-effective and the disease is almost universally fatal, but it's not a compelling use of resources.

Appreciate additional thoughts on this…

Take care

Tom Boo

Eastern Sierra

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